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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

5.Branding: 16.4 percent increase
“…fell asleep.”

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

plat平坦+form形状→形状平的地方→平台,月台
从2004年起,过去120年里的现代或当代艺术家们创作的10件作品在拍卖会上共卖出1亿多美元。而更早期绘画大师的作品价格则是稳中有跌。最近几周,这一趋势非常明显,伦敦的拍卖公司努力为自己的最新一批18世纪前绘画大师作品寻找买家。与近些年的情况一样,其中几乎没有名作。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

6.Head-Mounted Computer Displays

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

There's a crucial element in team building called planning that often seems to elude those franchises that are stuck in the mud.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

爆发冲突的潜在可能性,将迫使中国和美国在不断变幻的环境中重新定义各自的角色,双方都对这种环境感到不安。美国大选期间的反华情绪将使紧张气氛加剧。亚洲国家将勾勒出这两个大国的影响力范围,但考虑到各国的利益各有不同,取决于各自的具体关切,联盟的构成也将变化。
[k?'min]
根据FlightAware网站为福布斯编制的数据显示,总部位于落基山脉以西的航空公司在节假日期间的航班晚点率最低。
设在日内瓦的国际移民组织星期二公布的数字显示,一百万零五千五百零四名非洲和中东的流动人口,以非常规方式通过陆路和海路进入欧洲大陆,这个数字是2014年的四倍。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

shatter
Cross-cultural Instrumental performance (Yanni, USA, and Chang Jing)
Those born after 1995 tend to make more varied choices and are likely to combine work with their hobbies.
他也承认由于他和Vonnie已经离婚了所以听说这封信的时候感情有些复杂。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

It was the epoch of belief, it was the epoch of incredulity…

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 北京1月1日至5日暂停网签
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The media are annoying, we get that, Your Royal Highness, but there may have been more dignified ways for you (and the establishment you represent) to air your concerns.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Rank: 5
Over at Huffington Post Mark Gongloff warns: That 'dramatic downgrade of U.S. economic growth in the first quarter revealed the economy's lingering weakness, exposed the folly of Washington's austerity obsession and slapped the Federal Reserve's newfound optimism right in the face.' And with politics deteriorating, it'll get worse.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

从事房地产业的中国女富豪最多,占23%,金融投资业占18%,制造业占14%。
Meanwhile, New Yorkers living in the city’s nearly one million rent-stabilized apartments should brace for a fight in Albany in June, when the rent-stabilization law expires. Housing advocates hope to see a reversal of a rule that allows landlords to deregulate vacant units if the rent reaches $2,500 a month.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

中国2017年GDP增长预期目标为“6.5%左右”。
智能皮带

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

几年前,有人发明了一辆会飞的自行车,叫做"Paravelo"。称一辆自行车会飞,并不是开玩笑,而是这辆自行车真的会飞(车头有一个巨大的降落伞)。它在陆地和空中的时速分别为25千米(15英里)和40千米(25英里),可飞至1200米(4000英尺)高空。最棒的地方是什么呢?那就是你不需要有飞行驾照。Paravelo号称世界上第一辆会飞的自行车,但我们必须指出它并不是第一辆会飞的自行车。
Hannah Kuchler is San Francisco correspondent
But most of us are self-aware enough to understand that even as we do this, we are lying to ourselves. We recognize those dangers when it comes to politics (see: Bush and Clinton). Why should clothes be any different?
The consequences are more parochial than those of Chinese data distortion. British law requires the ONS to produce the RPI and, given that it refuses to improve the measure, its fiddling affects hundreds of billions of pounds of contracts which continue to be linked to the RPI.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 工信部力推新材料产业标准化
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

She made several points in a note to clients Tuesday that struck me as new:

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

10、日本8.5级地震
来自5个不同国家的5所商学院今年首次进入排行榜。新加坡李光前商学院(Lee Kong Chian School of Business)是新进入者中排名最高的,直接跃居第36位。加拿大女王大学史密斯商学院(Queen’s Smith School of Business)的排名提高最大,跃升32位至第67名。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

5、Poor e-mail communication

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Influenced by the current economic situation, and resource relocation in China's financial market, the banking industry is away from the high-speed growth period, the expert added.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 2016年石材行业关键词盘点
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

图表一显示的是上世纪70年代以来新兴市场银行、汇率及债务违约危机的发生次数——对照名义联邦基金利率。克普克以此为据,试图证明高位且不断上升的利率通常在新兴市场危机爆发周期之前出现。
15. An Amazing Coincidence One of the studios with the most on-screen diversity — it released “Trainwreck” and “Straight Outta Compton” (if also “Ted 2”) — and with the most female directors is Universal, which, as of early December, had gobbled up almost 24 percent of the year’s market share.
The 60-episode TV drama was adapted from a novel Legend of Princess Pearl published in 2007. It focuses on the protagonist Shen Zhenzhu’s romance with her husband and their efforts to protect the country.
New year’s events can be anticlimactic. Not so in China where stock markets began 2016 with enough excitement to make traders choke on their bubbles: Shanghai stocks dropped 7 per cent on Monday, Shenzhen more than 8 per cent. It could have been worse. A new mechanism that suspends trading after a drop of 7 per cent halted play early — in this instance, by an hour and a half.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

According to file-sharing news site TorrentFreak, "Game of Thrones" has an estimated 5.9 million downloads per single episode. That number does not include online streaming and cyberlocker downloads, which would make the figure significantly higher. By contrast, "Game of Thrones" has an estimated 5.5 million TV viewers per single episode。
泰勒·斯威夫特(Taylor Swift),《空白空间》(Blank Space), Big Machine
The world got by in 2013 with fewer confidence-shaking moments than in prior years. But the vulnerabilities haven't disappeared. 'It's not a great story anywhere, though it's more hopeful than it has been,' said Jerry Webman, chief economist at OppenheimerFunds.
第二晚(12月9日)的苏富比(Sotheby’s)拍卖会共拍得2260万英镑(含佣金),比佳士得前晚的表现要好得多,不过也只是略高于2180万英镑(不含佣金)的最低估价。44件拍品中有15件流拍,比例达34%。
根据中公教育(一家统计公务员报考人数的机构)的数据,在今年公务员考试报名的第六天,也就是周二,累计报考人数已超过45.96万,其中周一一天的报名人数几乎达到10.3万。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

以美元值计,11月中国的进口总值同比上升17.7%,比10月的17.2%高,高于11.3%的预期增速。
"This year's prize concerns a central economic problem: how to match different agents as well as possible," the academy said.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

The quickest growth in executive pay on average came from the hotel and catering sectors, at 47.58%.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

办公室总有一两个让人让大多数人都无法容忍的人,但是如果你不喜欢大多数的同事,那么你的工作就会变得不愉快因为你不得不整天和他们在一起工作。如果你再也不能容忍他们,试试找一个你能够和里面的职员和平相处的公司了。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

当你在求职布告栏比如Monster或者Indeed发布你的简历时,你现在的雇主是可有机会看到你的简历的。Foss说很多人事和经理经常在求职栏搜索职工的名字看他们是不是在找工作。
被调查的34个城市间的差距就更大了。北京市平均年终奖超过1.58万元人民币,超过了年终奖最低的沈阳市的三倍。沈阳市是中国东北铁锈地带辽宁省的省会。
上海金融学院的研究人员郭峰引用了周二华尔街见闻上的信息并表示,这也是自1978年中国改革开放以来,上海第一次见证了常住人口的减少 。
5. Geopolitical flashpoints.In the not too distant past, a small supply disruption would send oil prices skyward. In early 2014, for example, violence in Libya blocked oil exports, contributing to a rise in oil prices. In Iraq, ISIS overran parts of the country and oil prices shot up on fears of supply outages. But since then, geopolitical flashpoints have had much less of an effect on the price of crude. During the last few weeks of 2014, violence flared up again in Libya. But after a brief increase in prices, the markets shrugged off the event. Nevertheless, history has demonstrated time and again that geopolitical crises are some of the most powerful short-term movers of oil prices.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

'If you read Trigger Mortis, you’ll see actually there is a little twist to the tale in that particular story which I think sort of pays him off for his slightly patronising attitude.'
波尔图还有一系列较平民的博物馆、廉价的老式有轨电车和迷人的卵石海滩。葡萄园一日游这类短途旅行也非常便于安排。
昨日,108名表演者身着熊猫服装,穿行在伦敦的街头,向大众宣传这种惹人喜爱却面临灭绝危险的黑白物种。
Perhaps the more interesting question is what drove Yahoo! to shell out that reported $30 million for a single app. To be sure, Summly's text-compression abilities dovetail nicely with Yahoo!'s new focus on mobile utilities. Along with Yahoo!'s $1.1 billion purchase of the blogging service Tumblr and the launch of an acclaimed new weather app, the Summly move marks a commitment to owning the tiny real estate of the smartphone screen-and serving advertising to the youthful eyeballs that tend to gravitate to mobile devices.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

She argues, however, that the problems with lower liquidity of ETFs in Asia are a symptom of a fund distribution system that fails to incentivise ETF sales by intermediaries. “I don't think there is a quick fix, but you would see a pick-up if Asia moves to a fee-based model,” she says.
Entertainer of the year: Luke Bryan

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 租房如何避开“隐形杀手”?
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

他们必须发自内心地明白,通过操纵选举、打击异见或者骚扰反对派让临时权力永久化是不合法的。
Against: To some extent it's divided American audiences, perhaps damaging its hopes of winning best film.
In the past decade, only three blue diamonds of 10 carats or more with the same vivid grading for intensity have been sold at auction, all weighing less than 12 carats and none flawless, he said.
The 30 percent increase is to be driven bymore specialty drug innovation, greater patient access to medicines and reducedimpact from patent expiry dates.
A vibrant ETF market would depend on the evolution of fee-based distribution networks. Mark Talbot, managing director of Asia-Pacific at Fidelity International, says the distribution infrastructure is holding back retail demand.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Whiteness means being part of the group whose appearance, traditions, religion and even food are the default norm. It’s being a person who, by unspoken rules, was long entitled as part of “us” instead of “them.”
《她》(Her),由斯派克?琼斯(Spike Jonze)担任编剧兼导演,将浪漫带入了虚拟世界,影片的主人公展开了一场有些疯狂的真正激情之旅。华金?菲尼克斯(Joaquin Phoenix)扮演的男主角是个令人心酸的孤独小伙子,他爱上了自己智能手机的新操作系统。影片的基本构想有些脆弱,但故事非常华丽地展开,霍伊特?范?霍特玛(Hoyte Van Hoytema)的摄影也很精妙,完美地烘托了菲尼克斯、艾米?亚当斯(Amy Adams)和斯嘉丽?约翰逊(Scarlett Johansson)的表演。斯嘉丽?约翰逊在片中扮演的是智能手机操作系统的声音和灵魂。
"The average salary level of employees grew by about 6.3 percent year on year in the first three quarters of last year, while China's annual GDP growth stood at 6.7 percent in 2016, both slowing from a year earlier," Jin added.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

噢,卡梅隆,真希望你还有高中时的风采,因为那时的你是史诗般的存在。
但随着美国接近实现充分就业,随着通胀向目标水平趋近,“你可以看到收紧政策是有道理的,”他说,“不需要很多就足以改变整个平衡”。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 家居电商3岁 经营模式仍在探路
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

卓越雇主排名:1
赫洛维兹对爱尔兰广播公司RTE表示,他的新邦德形象强烈忠于50年代的邦德。
In the foreseeable future, China will see the boom of enterprises in tertiary industry. Related majors, including law, journalism and communication, and management, are expected to play a bigger role, according to the report.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Season\'s greetings and sincere wishes for a bright and happy New Year!
Those who graduated from Peking University and Beijing Foreign Studies University took second and third place, earning 9,042 yuan and 9,020 yuan a month, respectively.
但由于受到英国脱欧的影响,英镑大幅贬值,英国首相的收入换算成美元后也在大幅缩水。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 资产证券化成了长租公寓的毒药?
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

在如今的江苏省境内的贵族古墓里找到的。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

China’s commercial banks are the control centre of the financial system and supply almost 70% of the financing that feeds the real economy.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

5. Smart belt
10. 2012年搞笑诺贝尔奖之医学奖

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

唐同学怀疑水中被混合了有毒物质,便把此事报告给班长和老师。
Price is not everything, it is true. But even the bears would agree: everything has a price.
达洛伊西奥也尽力维持着生活原本的样子。他的女友还是之前的那个女友。而且尽管他不再去学校了──坐在教室里就没空监管Summly的研发──他还是照常去找老师拿作业。他十分庆幸他的朋友不了解他企业家的那一面。而当我采访他的时候,他正准备和一群高中死党去希腊玩上一周。
最近,无人驾驶汽车的新闻屡见报端,它也叫做自动驾驶汽车。谷歌的自动驾驶汽车是此行业的领头羊,已行驶48万千米(30万英里),仅发生过两次交通事故,还都是人为因素造成的。事实上,无人驾驶汽车并不是新奇事物,早在达·芬奇发明以弹簧发条作驱动带内置预设程序的马车时,自动驾驶的概念便名噪一时。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

夏奇拉
●“Girl Infects 586 Men With HIV On Purpose, Plans On Infecting 2,000 More Before 2017 - TRENDING”

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

一些英国退欧派人士和共和党人相信绝对自由市场理念,
2. 《头脑特工队》,导演:彼得·道格特(Pete Docter)。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

下面是今年最令人难忘的四个设计,包括参与塑造这些造型的一些艺术家们的评论。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

于上周二发布的《2016胡润IT富豪榜》显示,排在前50名的中国IT富豪的平均财富同比上涨13%,至创纪录的269亿元。
transportation
The Belty is great that it uses technology to track fitness, water intake, and posture, but for $395, you might be better off getting the same in a stylish smart watch or activity tracker.
9. 设身处地也能提高记忆力

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

It is revealed that Hadid's visa application was turned down after she offended many by squinting her eyes in an attempt to impersonate the Buddha in February.
政治建军、改革强军、依法治军

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

中国迅猛发展的网红经济历经了3个阶段——第一阶段基于语言文字,第二阶段是文字加图片,现在由于宽带网络的可获得性,第三阶段就是视频。
It is said in the report that the three major industries that graduates expected to work for are it/internet/telecommunications/electronics industry, financial industry/ banking/investment/fund/securities/insurance, government/public service/non-profit-making institutions.
The research also suggests there maybe a value in finding a job through an internship. Interns who accepted a job offer had higher salaries than those who had received an offer but refused it. Those interns who did not receive an offer had lower salaries still. The gap between these groups had increased three years after graduation.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 长租公寓需求上涨,品质参差不齐
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

今年1月份CPI同比上涨1.8%,去年12月同比上涨为1.6%。不过该指数仍落后于北京方面“3%左右”的目标。
In 2018, more business leaders will channel a potent combination of digitalisation, generational change and growing diversity, to streamline their hierarchies, distribute responsibility, and transform their organisations.
这些利好消息为特斯拉带来了极为惊人的估值。一位名叫佐尔坦o班的特斯拉观察人士在金融网站“寻找阿尔法“(Seeking Alpha)上指出,特斯拉现在的估值,相当于它每年已经能够卖出几十万辆汽车,但实际上今年它只能卖出35,000多辆车。从另一个角度来说,特斯拉公司今年卖出的每一台车,估值相当于高达100万美元。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

林浩文预测称,市场的任何复苏都将倚赖来自资金充沛的内地公司的需求,同时外国投资者将仅限于投资于房地产投资信托或者涉及地产开发商的股票,而不会真的买入房产。
最佳迷你剧集/电影类导演:苏珊娜?比埃尔(Susanne Bier),《夜班经理》(The Night Manager)

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 4G牌照颁布 智能家居坐上特快列车
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 荣麟家居启动线上打假
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 北京潞城棚改首批安置房4月交付
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

节目4 小品《我要上春晚》,周炜 刘大成 石头 张尧等
It is a timely warning. His findings, he writes, “point to a heightened risk of emerging market crises in the coming years as the Fed continues to normalise interest rates”.
我国火车票购票官网12306网站已成为世界最大火车票购票网站,2017年该网站交易总量达35亿张车票。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 北京11月首套房贷款平均利率5.47%
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

"We have a system here in America where if something is for you and if they find it, it gets to you, that's beautiful," he told US TV station WTAE.
How has your trip to the US sofar this summer?

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 儿童家具环保、安全规范势在必行
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

adj. 傲慢的,自大的
8. 亚马逊的自助出版工具
排名:第五

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

如果没有别的,很明显,夏天交易期并不代表NBA赛季的停止,它只是换了个档而已。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Financial success and dazzling new technology alone might have been enough to earn Apple’s steely chief executive the FT’s vote as the 2014 Person of the Year, but Mr Cook’s brave exposition of his values also sets him apart.
Online sales contributed 82.6 percent of sales. Online sales have prompted traditional stores, including 13 of Beijing's 77 "time-honored brands" from snack stores to shoes sellers, to move their goods online.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

"I have school tomorrow, so I can't stay up late," she told the paper.
[t?ek]

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

n. 奇思妙想,一段楼
1.《宋飞正传》"踢脚舞"一集差点流产

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 中国人保11日早盘再度跌停
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

正当整个时尚界都在为拉格菲尔德哀悼,而除了他的众多继承人,他的爱猫邱佩特可能也会继承他的1.5亿英镑财产的一部份。
SETTING: This house is in Kenwood, a neighborhood of 19th- and 20th-century Tudors, Mediterraneans, Victorians and colonial-style houses between Cedar Lake and Lake of the Isles, in the city’s Chain of Lakes. Roads are curving; sidewalks are lined with maple and ash trees. According to the listing agent, many of the neighborhood’s older houses have been restored, while houses built within the last 30 years have been torn down and replaced.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

中国的网红经济发展到今天,经历了三个阶段:第一个阶段是文字时代,第二个阶段是图文时代,现在这一阶段是要归功于宽带的可用性的视频时代。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

As for his own education: He's weighing whether to enroll in university in England or maybe the U.S. to be closer to Silicon Valley. Or perhaps he'll skip college entirely and just focus on his work. 'I absolutely want to start another company,' he says. 'Serial entrepreneurs get addicted to creation. I want to be passionate. I feel really bad when I'm not doing something new.'
小说作者安东尼·赫洛维兹(Anthony Horowitz)透露,新书《Trigger Mortis》为现代读者作了改动,包含反对吸烟的信息,而且首次有一位“直言不讳”的同性恋朋友出场。
2016年上半年,《实验心理学》期刊刊登了一项研究,题为“绘画效应:帮你在无障碍回忆的过程中构筑可靠强大的记忆力”。虽然这篇文章的题目看起来有点长、有点复杂,但是它证明的观点其实很简单,即把单词画出来的记忆方式能够建立更为优质牢固的记忆。研究的主持人进行了一个简单任务实验,在实验中,一位参与者要求画出简单的单词,比如常见的水果,接着,他被要求回忆自己画的是些什么单词。另一些参与者被要求重复朗读给出的单词。
The PPI fell 5.3 per cent year-on-year in January, moderating from December’s -5.9 per cent pace. PPI has remained in negative territory since March 2012, reaching a low of -5.9 per cent for the five consecutive months since August 2015.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 不必改为个人收入调节税
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

她和妹妹都是通过家庭辅导接受教育的。她的妹妹也出演了《Dance Moms》。去年,以两姐妹的名字创建的时尚品牌The Maddie & Mackenzie Collection问世。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

创业会对创业者的个人生活造成严重影响。虽然上面的建议对创业成功至关重要,但从精神和身体上照顾好自己同样是必要的。锻炼、睡眠和饮食是确保你成功执行这些策略的关键要素。这些要素能够帮助你调整心态,获得动力,拓展人际关系。
长话短说,1772年圣诞节后,Seppenwolde很快就破产了。这场灾难是当时荷兰报纸的头条新闻。它彻底毁了阿姆斯特丹一批商人和银行家。为了防止出现全面的信贷崩溃,阿姆斯特丹市只能作为最后贷款人暂时介入。这种情形是不是似曾相识?
A panel of eight WardsAuto editors evaluated 44 engines among all vehicle types during October and November in the course of their daily commutes and weekend activities in and around the Detroit metro area. Engines were rated according to a wide range of characteristics including horsepower and torque, fuel economy, noise, vibration and harshness characteristics, technology and how they fared against competing powerplants.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

The Warriors and Timberwolves will arrive in Shenzhen on Oct 5 and will play at the Shenzhen Universiade Center.
FOYLE’S WAR (acorn.tv, Feb. 2) After nabbing the final three episodes of “Agatha Christie’s Poirot” last year, the streaming service Acorn TV scores another coup in the field of traditional British mysteries with the American premiere of this superior show’s ninth season. Starring Michael Kitchen as Christopher Foyle, a detective as honorable as he is shrewd, the series has morphed over the years from a provincial home-front cop show to a le Carré-like Cold War thriller. New episodes involve the Nuremberg trials and Britain’s role in Palestine.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Dirk Philippa, portfolio manager of Fidelity International’s global property fund, has also cut investments in Hong Kong from a 6-8 per cent overweight two years ago, relative to benchmarks, to a 1 per cent overweight position.
根据报道,当地法院鉴于周某的年龄及其坦白承认自己的罪行,最终给予了周某一个宽大的判决。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

“写这本书的一大挑战是异性恋男人能改变一个女人的生活并使她死心塌地的看法。”

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Foreigners with permanent residence enjoy the same rights as Chinese citizens, such as in investment, housing purchases and schooling, among other rights.
And the best gig for 2015? That would be an actuary, the people who specialize in financial risk.
6. “The Martian” With its red-rock buttes and mesas, Ridley Scott’s deeply satisfying space western both draws from an enduring genre and his own Pantheon legacy. (Read the review.)

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

The worst of 2015
8.Prosthetic Hands That Sense Touch
Do you feel any of your worksare underrated or wished was a little bit more popular?
1=不全是

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 2015年1-11月防水行业的经济分析
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

The fall in profits in December highlights the challenges facing an industrial sector racked by overcapacity and falling prices, adding to pressure on authorities to loosen monetary policy and boost infrastructure spending to cushion the slowdown.
大师级别的老式、线性的动作电影拍摄,充满污秽、朋克、反乌托邦的澳大利亚式幽默。也是最近除玛格丽特·阿斯特伍德(Margaret Atwood)的小说之外,最好的生态-女权-社会主义作品。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

一只五人帅哥音乐剧组合Callabro赢得了大众的青睐,赢得了最高选票,成功卫冕。与此同时,他们还获得了250,000英镑的现金奖励,还获得一次在皇家面前表演的机会。
两乐设备是青铜做的可以追溯到2000多年前中国的汉朝(公元前206年–公元220)。
根据中国海关总署(General Administration of Customs)的数据,在经历了此前一个月的同比下跌1.4%之后,11月份中国的进口同比增长6.7%,至1522亿美元,远高于同比收缩1.9%的预测中值。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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1.Fingers That Store Digital Files
《大唐荣耀》

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