Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
5.Branding: 16.4 percent increase
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
6.Head-Mounted Computer Displays
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
There's a crucial element in team building called planning that often seems to elude those franchises that are stuck in the mud.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Trends and targets in antiviral phototherapy
Cross-cultural Instrumental performance (Yanni, USA, and Chang Jing)
Those born after 1995 tend to make more varied choices and are likely to combine work with their hobbies.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
It was the epoch of belief, it was the epoch of incredulity…
Novel biosensing methodologies for ultrasensitive detection of viruses
The media are annoying, we get that, Your Royal Highness, but there may have been more dignified ways for you (and the establishment you represent) to air your concerns.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Over at Huffington Post Mark Gongloff warns: That 'dramatic downgrade of U.S. economic growth in the first quarter revealed the economy's lingering weakness, exposed the folly of Washington's austerity obsession and slapped the Federal Reserve's newfound optimism right in the face.' And with politics deteriorating, it'll get worse.
ACE2 as a potential therapeutic target for pandemic COVID-19
Meanwhile, New Yorkers living in the city’s nearly one million rent-stabilized apartments should brace for a fight in Albany in June, when the rent-stabilization law expires. Housing advocates hope to see a reversal of a rule that allows landlords to deregulate vacant units if the rent reaches $2,500 a month.
Diagnostic technologies for COVID-19: a review
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Hannah Kuchler is San Francisco correspondent
But most of us are self-aware enough to understand that even as we do this, we are lying to ourselves. We recognize those dangers when it comes to politics (see: Bush and Clinton). Why should clothes be any different?
The consequences are more parochial than those of Chinese data distortion. British law requires the ONS to produce the RPI and, given that it refuses to improve the measure, its fiddling affects hundreds of billions of pounds of contracts which continue to be linked to the RPI.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
She made several points in a note to clients Tuesday that struck me as new:
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
来自5个不同国家的5所商学院今年首次进入排行榜。新加坡李光前商学院(Lee Kong Chian School of Business)是新进入者中排名最高的，直接跃居第36位。加拿大女王大学史密斯商学院(Queen’s Smith School of Business)的排名提高最大，跃升32位至第67名。
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
5、Poor e-mail communication
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Influenced by the current economic situation, and resource relocation in China's financial market, the banking industry is away from the high-speed growth period, the expert added.
Antiviral drug discovery: broad-spectrum drugs from nature
15. An Amazing Coincidence One of the studios with the most on-screen diversity — it released “Trainwreck” and “Straight Outta Compton” (if also “Ted 2”) — and with the most female directors is Universal, which, as of early December, had gobbled up almost 24 percent of the year’s market share.
The 60-episode TV drama was adapted from a novel Legend of Princess Pearl published in 2007. It focuses on the protagonist Shen Zhenzhu’s romance with her husband and their efforts to protect the country.
New year’s events can be anticlimactic. Not so in China where stock markets began 2016 with enough excitement to make traders choke on their bubbles: Shanghai stocks dropped 7 per cent on Monday, Shenzhen more than 8 per cent. It could have been worse. A new mechanism that suspends trading after a drop of 7 per cent halted play early — in this instance, by an hour and a half.
Influenza neuraminidase: A druggable target for natural products
According to file-sharing news site TorrentFreak, "Game of Thrones" has an estimated 5.9 million downloads per single episode. That number does not include online streaming and cyberlocker downloads, which would make the figure significantly higher. By contrast, "Game of Thrones" has an estimated 5.5 million TV viewers per single episode。
泰勒·斯威夫特(Taylor Swift)，《空白空间》(Blank Space)， Big Machine
The world got by in 2013 with fewer confidence-shaking moments than in prior years. But the vulnerabilities haven't disappeared. 'It's not a great story anywhere, though it's more hopeful than it has been,' said Jerry Webman, chief economist at OppenheimerFunds.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
"This year's prize concerns a central economic problem: how to match different agents as well as possible," the academy said.
The role of biosensors in the detection of emerging infectious diseases
The quickest growth in executive pay on average came from the hotel and catering sectors, at 47.58%.
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
5. Geopolitical flashpoints.In the not too distant past, a small supply disruption would send oil prices skyward. In early 2014, for example, violence in Libya blocked oil exports, contributing to a rise in oil prices. In Iraq, ISIS overran parts of the country and oil prices shot up on fears of supply outages. But since then, geopolitical flashpoints have had much less of an effect on the price of crude. During the last few weeks of 2014, violence flared up again in Libya. But after a brief increase in prices, the markets shrugged off the event. Nevertheless, history has demonstrated time and again that geopolitical crises are some of the most powerful short-term movers of oil prices.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
'If you read Trigger Mortis, you’ll see actually there is a little twist to the tale in that particular story which I think sort of pays him off for his slightly patronising attitude.'
Perhaps the more interesting question is what drove Yahoo! to shell out that reported $30 million for a single app. To be sure, Summly's text-compression abilities dovetail nicely with Yahoo!'s new focus on mobile utilities. Along with Yahoo!'s $1.1 billion purchase of the blogging service Tumblr and the launch of an acclaimed new weather app, the Summly move marks a commitment to owning the tiny real estate of the smartphone screen-and serving advertising to the youthful eyeballs that tend to gravitate to mobile devices.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
She argues, however, that the problems with lower liquidity of ETFs in Asia are a symptom of a fund distribution system that fails to incentivise ETF sales by intermediaries. “I don't think there is a quick fix, but you would see a pick-up if Asia moves to a fee-based model,” she says.
Entertainer of the year: Luke Bryan
Inhibition of SARS coronavirus helicase by bismuth complexes
Against: To some extent it's divided American audiences, perhaps damaging its hopes of winning best film.
In the past decade, only three blue diamonds of 10 carats or more with the same vivid grading for intensity have been sold at auction, all weighing less than 12 carats and none flawless, he said.
The 30 percent increase is to be driven bymore specialty drug innovation, greater patient access to medicines and reducedimpact from patent expiry dates.
A vibrant ETF market would depend on the evolution of fee-based distribution networks. Mark Talbot, managing director of Asia-Pacific at Fidelity International, says the distribution infrastructure is holding back retail demand.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Whiteness means being part of the group whose appearance, traditions, religion and even food are the default norm. It’s being a person who, by unspoken rules, was long entitled as part of “us” instead of “them.”
《她》(Her)，由斯派克?琼斯(Spike Jonze)担任编剧兼导演，将浪漫带入了虚拟世界，影片的主人公展开了一场有些疯狂的真正激情之旅。华金?菲尼克斯(Joaquin Phoenix)扮演的男主角是个令人心酸的孤独小伙子，他爱上了自己智能手机的新操作系统。影片的基本构想有些脆弱，但故事非常华丽地展开，霍伊特?范?霍特玛(Hoyte Van Hoytema)的摄影也很精妙，完美地烘托了菲尼克斯、艾米?亚当斯(Amy Adams)和斯嘉丽?约翰逊(Scarlett Johansson)的表演。斯嘉丽?约翰逊在片中扮演的是智能手机操作系统的声音和灵魂。
"The average salary level of employees grew by about 6.3 percent year on year in the first three quarters of last year, while China's annual GDP growth stood at 6.7 percent in 2016, both slowing from a year earlier," Jin added.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
In the foreseeable future, China will see the boom of enterprises in tertiary industry. Related majors, including law, journalism and communication, and management, are expected to play a bigger role, according to the report.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Season\'s greetings and sincere wishes for a bright and happy New Year!
Those who graduated from Peking University and Beijing Foreign Studies University took second and third place, earning 9,042 yuan and 9,020 yuan a month, respectively.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
China’s commercial banks are the control centre of the financial system and supply almost 70% of the financing that feeds the real economy.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
5. Smart belt
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Price is not everything, it is true. But even the bears would agree: everything has a price.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
●“Girl Infects 586 Men With HIV On Purpose, Plans On Infecting 2,000 More Before 2017 - TRENDING”
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
2. 《头脑特工队》，导演：彼得·道格特(Pete Docter)。
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
The Belty is great that it uses technology to track fitness, water intake, and posture, but for $395, you might be better off getting the same in a stylish smart watch or activity tracker.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
It is revealed that Hadid's visa application was turned down after she offended many by squinting her eyes in an attempt to impersonate the Buddha in February.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
It is said in the report that the three major industries that graduates expected to work for are it/internet/telecommunications/electronics industry, financial industry/ banking/investment/fund/securities/insurance, government/public service/non-profit-making institutions.
The research also suggests there maybe a value in finding a job through an internship. Interns who accepted a job offer had higher salaries than those who had received an offer but refused it. Those interns who did not receive an offer had lower salaries still. The gap between these groups had increased three years after graduation.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
In 2018, more business leaders will channel a potent combination of digitalisation, generational change and growing diversity, to streamline their hierarchies, distribute responsibility, and transform their organisations.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
最佳迷你剧集/电影类导演：苏珊娜?比埃尔(Susanne Bier)，《夜班经理》(The Night Manager)
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
节目4 小品《我要上春晚》，周炜 刘大成 石头 张尧等
It is a timely warning. His findings, he writes, “point to a heightened risk of emerging market crises in the coming years as the Fed continues to normalise interest rates”.
A modular microarray imaging system for highly specific COVID-19 antibody testing
"We have a system here in America where if something is for you and if they find it, it gets to you, that's beautiful," he told US TV station WTAE.
How has your trip to the US sofar this summer?
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Financial success and dazzling new technology alone might have been enough to earn Apple’s steely chief executive the FT’s vote as the 2014 Person of the Year, but Mr Cook’s brave exposition of his values also sets him apart.
Online sales contributed 82.6 percent of sales. Online sales have prompted traditional stores, including 13 of Beijing's 77 "time-honored brands" from snack stores to shoes sellers, to move their goods online.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
"I have school tomorrow, so I can't stay up late," she told the paper.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
SETTING: This house is in Kenwood, a neighborhood of 19th- and 20th-century Tudors, Mediterraneans, Victorians and colonial-style houses between Cedar Lake and Lake of the Isles, in the city’s Chain of Lakes. Roads are curving; sidewalks are lined with maple and ash trees. According to the listing agent, many of the neighborhood’s older houses have been restored, while houses built within the last 30 years have been torn down and replaced.
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
As for his own education: He's weighing whether to enroll in university in England or maybe the U.S. to be closer to Silicon Valley. Or perhaps he'll skip college entirely and just focus on his work. 'I absolutely want to start another company,' he says. 'Serial entrepreneurs get addicted to creation. I want to be passionate. I feel really bad when I'm not doing something new.'
小说作者安东尼·赫洛维兹（Anthony Horowitz）透露，新书《Trigger Mortis》为现代读者作了改动，包含反对吸烟的信息，而且首次有一位“直言不讳”的同性恋朋友出场。
The PPI fell 5.3 per cent year-on-year in January, moderating from December’s -5.9 per cent pace. PPI has remained in negative territory since March 2012, reaching a low of -5.9 per cent for the five consecutive months since August 2015.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
她和妹妹都是通过家庭辅导接受教育的。她的妹妹也出演了《Dance Moms》。去年，以两姐妹的名字创建的时尚品牌The Maddie & Mackenzie Collection问世。
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
A panel of eight WardsAuto editors evaluated 44 engines among all vehicle types during October and November in the course of their daily commutes and weekend activities in and around the Detroit metro area. Engines were rated according to a wide range of characteristics including horsepower and torque, fuel economy, noise, vibration and harshness characteristics, technology and how they fared against competing powerplants.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
The Warriors and Timberwolves will arrive in Shenzhen on Oct 5 and will play at the Shenzhen Universiade Center.
FOYLE’S WAR (acorn.tv, Feb. 2) After nabbing the final three episodes of “Agatha Christie’s Poirot” last year, the streaming service Acorn TV scores another coup in the field of traditional British mysteries with the American premiere of this superior show’s ninth season. Starring Michael Kitchen as Christopher Foyle, a detective as honorable as he is shrewd, the series has morphed over the years from a provincial home-front cop show to a le Carré-like Cold War thriller. New episodes involve the Nuremberg trials and Britain’s role in Palestine.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Dirk Philippa, portfolio manager of Fidelity International’s global property fund, has also cut investments in Hong Kong from a 6-8 per cent overweight two years ago, relative to benchmarks, to a 1 per cent overweight position.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
Foreigners with permanent residence enjoy the same rights as Chinese citizens, such as in investment, housing purchases and schooling, among other rights.
And the best gig for 2015? That would be an actuary, the people who specialize in financial risk.
6. “The Martian” With its red-rock buttes and mesas, Ridley Scott’s deeply satisfying space western both draws from an enduring genre and his own Pantheon legacy. (Read the review.)
Length-scale dependence of protein hydration-shell density
The worst of 2015
8.Prosthetic Hands That Sense Touch
Do you feel any of your worksare underrated or wished was a little bit more popular?
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
The fall in profits in December highlights the challenges facing an industrial sector racked by overcapacity and falling prices, adding to pressure on authorities to loosen monetary policy and boost infrastructure spending to cushion the slowdown.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
根据中国海关总署(General Administration of Customs)的数据，在经历了此前一个月的同比下跌1.4%之后，11月份中国的进口同比增长6.7%，至1522亿美元，远高于同比收缩1.9%的预测中值。
About this collection
1.Fingers That Store Digital Files